Description

2'-Chloro-3-(3,4,5-trifluorophenyl)propiophenone is a high-value fluorinated aromatic ketone intermediate, essential for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. Its unique trifluoromethylphenyl and propiophenone structure makes it a critical building block for developing compounds with enhanced biological activity and metabolic stability. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral medications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms contribute to improved lipophilicity and target binding.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in organic chemistry research to construct complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding and applying fluorination effects in molecular design.

Basic Information

Product Name	2'-Chloro-3-(3,4,5-trifluorophenyl)propiophenone
CAS No.	898778-24-0
Molecular Formula	C15H9ClF3O
Molecular Weight	306.68 g/mol
Synonyms	1-(2-Chlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 2'-Chloro-3,4,5-trifluoropropiophenone; 3-(3,4,5-Trifluorophenyl)-1-(2-chlorophenyl)propan-1-one; 898778-24-0; Propiophenone, 2'-chloro-3-(3,4,5-trifluorophenyl)-; 1-Propanone, 1-(2-chlorophenyl)-3-(3,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2'-Chloro-3-(3,4,5-trifluorophenyl)propiophenone is produced and tested under a strict quality management system. We ensure compliance with cGMP guidelines where applicable, providing full traceability and documentation. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.