Description

2',4'-Dimethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring a trifluoromethylphenyl moiety, makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms contribute to improved lipophilicity and target binding.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorinated structure.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or host materials in display technologies.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and exploring new fluorination chemistry pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2',4'-Dimethyl-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-00-2
Molecular Formula	C17H15F3O
Molecular Weight	292.30 g/mol
Synonyms	1-(2,4-Dimethylphenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(2,4-dimethylphenyl)propan-1-one; 2,4-Dimethyl-3'-(3,4,5-trifluorophenyl)propiophenone; Propiophenone, 2',4'-dimethyl-3-(3,4,5-trifluorophenyl)-; 898778-00-2; (3,4,5-Trifluorophenyl)-2,4-dimethylpropiophenone
EINECS	Contact for details

Quality Control

Our 2',4'-Dimethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light) and should be kept under inert atmosphere for long-term storage to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.