Description

4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate, distinguished by its unique polyfluorinated phenyl and propiophenone structure. This compound is critical for its role in synthesizing advanced pharmaceutical and agrochemical molecules, where its fluorine atoms enhance metabolic stability and binding affinity. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging fluorine's properties to improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis & Catalysis Research: A valuable substrate for methodological studies in cross-coupling and fluorination chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Item	Detail
Product Name	4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898777-96-3
Molecular Formula	C15H9F4O
Molecular Weight	272.23 g/mol
Synonyms	1-(4-Fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3',4',5',4-Tetrafluoro-3-phenylpropiophenone; 4-Fluoro-3-(3,4,5-trifluorobenzyl)propiophenone; 898777-96-3; Propiophenone, 4'-fluoro-3-(3,4,5-trifluorophenyl)-; 3-(3,4,5-Trifluorophenyl)-1-(4-fluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Every batch of 4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects with material suitable for research use through to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.