Description

4'-Chloro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound is valued for its unique trifluoromethylphenyl and propiophenone structure, which serves as a critical building block for creating complex molecules with tailored properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a core structure for electron-transporting or host materials in OLED device fabrication.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, such as cross-coupling reactions and fluorination studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4'-Chloro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898777-92-9
Molecular Formula	C15H9ClF3O
Molecular Weight	306.68 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3',4',5'-Trifluoro-4-chloropropiophenone; 4-Chloro-3'4'5'-trifluoropropiophenone; Propiophenone, 4'-chloro-3-(3,4,5-trifluorophenyl)-; 898777-92-9; 4'-Chloro-3'4'5'-trifluoropropiophenone; 1-(4-Chlorophenyl)-3-(3,4,5-trifluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.