Description

4'-Cyano-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a cyano group and a trifluoromethylphenyl moiety, makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices due to its electronic properties.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel polymers and functional materials with specific optical or electronic characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	4'-Cyano-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898777-74-7
Molecular Formula	C₁₆H₉F₃NO
Molecular Weight	288.25 g/mol
Synonyms	1-[4-Cyanophenyl]-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(4-cyanophenyl)propan-1-one; 4-Cyano-3'-(3,4,5-trifluorophenyl)propiophenone; 4'-Cyano-3-(3,4,5-trifluorophenyl)propiophenone; Propiophenone, 4'-cyano-3-(3,4,5-trifluorophenyl)-; 898777-74-7; 3,4,5-Trifluorophenyl 4-cyanopropiophenone
EINECS	Contact for details

Quality Control

Our 4'-Cyano-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.