Description

2'-Methoxy-3-(3,4,5-trifluorophenyl)propiophenone is a high-value fluorinated aromatic ketone intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, where the trifluoromethylphenyl moiety and propiophenone backbone are key structural features. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Material Science Chemistry: Serves as a monomer or building block for synthesizing specialized polymers and advanced organic materials with unique electronic or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and fluorination studies to create diverse chemical libraries for high-throughput screening.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis manufacturers for client-specific projects and scale-up development.

Basic Information

Product Name	2'-Methoxy-3-(3,4,5-trifluorophenyl)propiophenone
CAS No.	898777-64-5
Molecular Formula	C₁₆H₁₃F₃O₂
Molecular Weight	294.27 g/mol
Synonyms	1-(2-Methoxyphenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(2-methoxyphenyl)propan-1-one; 2'-Methoxy-3,4,5-trifluoropropiophenone; 2-Methoxy-β-(3,4,5-trifluorophenyl)propiophenone; Propiophenone, 2'-methoxy-3-(3,4,5-trifluorophenyl)-; 898777-64-5; 2'-Methoxy-3-(3,4,5-trifluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Every batch of 2'-Methoxy-3-(3,4,5-trifluorophenyl)propiophenone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications tailored to meet project-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.