Description

4'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring a trifluoromethylphenyl moiety, makes it a critical building block for the development of complex, bioactive molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated organic electronic materials due to its stable aromatic structure.
• Advanced Organic Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing complex polycyclic aromatic systems in academic and industrial R&D.
• Fluorine Chemistry Studies: Utilized as a model compound for investigating the effects of polyfluorination on reaction kinetics and molecular properties.

Basic Information

Product Name	4'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898777-62-3
Molecular Formula	C16H13F3O
Molecular Weight	278.27 g/mol
Synonyms	1-(4-Methylphenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3',4',5'-Trifluoro-4-methylpropiophenone; 3-(3,4,5-Trifluorophenyl)-1-(p-tolyl)propan-1-one; 4-Methyl-3'4'5'-trifluoropropiophenone; Propiophenone, 4'-methyl-3-(3,4,5-trifluorophenyl)-; 898777-62-3; 4'-Methyl-3-(3,4,5-trifluorophenyl)propiophenone
EINECS	Contact for details

Quality Control

Our production of 4'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.