Description

3'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate, distinguished by its unique trifluoromethylphenyl substitution pattern. This compound is critical for its role in synthesizing advanced pharmaceutical and agrochemical active ingredients, where its fluorine atoms enhance metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the fine chemical and life science industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty monomers and ligands used in advanced polymer and catalyst development.
• Organic Synthesis & Medicinal Chemistry: A versatile scaffold for constructing complex molecular architectures in drug discovery and lead optimization programs.
• Fluorine Chemistry Studies: Employed as a model compound in academic and industrial research to study the effects of polyfluorination on chemical reactivity and physical properties.

Basic Information

Product Name	3'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898777-60-1
Molecular Formula	C16H13F3O
Molecular Weight	278.27 g/mol
Synonyms	1-(3-Methylphenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3'-Methyl-3-(3,4,5-trifluorophenyl)-1-propiophenone; 3,4,5-Trifluoro-3'-(methyl)propiophenone; 3-(3,4,5-Trifluorophenyl)-1-(m-tolyl)propan-1-one; m-Tolyl 3-(3,4,5-trifluorophenyl)propyl ketone; Propiophenone, 3'-methyl-3-(3,4,5-trifluorophenyl)-; 898777-60-1
EINECS	Contact for details

Quality Control

Our production of 3'-Methyl-3-(3,4,5-Trifluorophenyl)Propiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive identity confirmation and impurity profiling. Certificates of Analysis (COA) detailing purity, assay, and specific impurity limits are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.