Description

3',5'-Difluoro-3-(4-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block, identified by CAS NO 898776-43-7. This compound is valued for its precise molecular structure, which serves as a critical intermediate in the synthesis of complex, biologically active molecules. It is primarily required by research institutions and pharmaceutical development companies engaged in the discovery and production of new active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the stability imparted by the fluorine atoms.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals where specific fluorine-substituted aromatic structures are required.
• Organic Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing complex fluorinated heterocycles in academic and industrial R&D.
• Fluorine Chemistry Studies: Utilized as a reference standard or reactant in studies exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	3',5'-Difluoro-3-(4-Methoxyphenyl)Propiophenone
CAS No.	898776-43-7
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3-(4-methoxyphenyl)-1-propanone; 3-(4-Methoxyphenyl)-1-(3,5-difluorophenyl)propan-1-one; 3',5'-Difluoro-3-(4-methoxyphenyl)propiophenone; 898776-43-7; Propiophenone, 3',5'-difluoro-3-(4-methoxyphenyl)-; 3-(4-Methoxyphenyl)-1-(3,5-difluorophenyl)propanone
EINECS	Contact for details

Quality Control

Our production of 3',5'-Difluoro-3-(4-Methoxyphenyl)Propiophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.