Description

3',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate. This compound is critical for its role in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients. Its specific substitution pattern offers unique reactivity and physicochemical properties essential for modern drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, where the difluoro and methoxy groups contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals, leveraging its rigid aromatic backbone and fluorine atoms.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, carbonyl chemistry, and fluorination studies within academic and industrial research laboratories.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on aromatic systems and reaction pathways.

Basic Information

Product Name	3',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone
CAS No.	898776-40-4
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(4-methoxyphenyl)propan-1-one; 3-(4-Methoxyphenyl)-1-(3,4-difluorophenyl)propan-1-one; 3,4-Difluoro-3'-(4-methoxyphenyl)propiophenone; 898776-40-4; Propiophenone, 3',4'-difluoro-3-(4-methoxyphenyl)-; 3-(4-Methoxyphenyl)-1-(3,4-difluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.