Description

2',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate, recognized for its role in advanced organic synthesis. Its molecular structure, featuring both difluoro and methoxyphenyl substituents, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new fluorination methodologies and catalytic processes in academic and industrial R&D.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	2',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone
CAS No.	898776-37-9
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	1-(2,4-Difluorophenyl)-3-(4-methoxyphenyl)propan-1-one; 3-(4-Methoxyphenyl)-1-(2,4-difluorophenyl)propan-1-one; 2,4-Difluoro-3'-(4-methoxyphenyl)propiophenone; 898776-37-9; Propiophenone, 2',4'-difluoro-3-(4-methoxyphenyl)-; 1-(2,4-Difluorophenyl)-3-(4-methoxyphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Every batch of 2',4'-Difluoro-3-(4-Methoxyphenyl)Propiophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Incompatible with strong alkalis and fluorinating agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.