Description

3-Fluoro-4'-Pyrrolidinomethyl Benzophenone is a high-purity, functionalized benzophenone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique fluorinated pyrrolidine motif into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the benzophenone core provides photostability and bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or mechanical properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research due to its reactive ketone group.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.
• Fine Chemical Synthesis: Utilized in multi-step syntheses of complex organic molecules for various high-value industrial applications.

Basic Information

Product Name	3-Fluoro-4'-Pyrrolidinomethyl Benzophenone
CAS No.	898776-35-7
Molecular Formula	C18H18FNO
Molecular Weight	283.34 g/mol
Synonyms	3-Fluoro-4'-(pyrrolidin-1-ylmethyl)benzophenone; (3-Fluorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone; 1-({4-[(3-Fluorobenzoyl)phenyl]methyl})pyrrolidine; Benzophenone, 3-fluoro-4'-(pyrrolidinylmethyl)-; 898776-35-7; 3-Fluoro-4'-pyrrolidin-1-ylmethylbenzophenone
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4'-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.