Description

2'-Chloro-4'-Fluoro-3-(4-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and methoxy-substituted aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders, inflammatory conditions, and metabolic diseases.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for studying cross-coupling reactions, carbonyl chemistry, and the development of new synthetic methodologies.
• Agrochemical Development: Serves as a precursor in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Investigated as a monomer or precursor for specialty polymers and liquid crystals due to its rigid, substituted aromatic core.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(4-Methoxyphenyl)Propiophenone
CAS No.	898776-13-1
Molecular Formula	C16H14ClFO2
Molecular Weight	292.73 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-(4-methoxyphenyl)propan-1-one; 3-(4-Methoxyphenyl)-1-(2-chloro-4-fluorophenyl)propan-1-one; 2-Chloro-4-fluoro-3'-(4-methoxyphenyl)propiophenone; Propiophenone, 2'-chloro-4'-fluoro-3-(4-methoxyphenyl)-; 898776-13-1; 2'-Chloro-4'-fluoro-3-(4-methoxyphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our production of 2'-Chloro-4'-Fluoro-3-(4-Methoxyphenyl)Propiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.