Description

3-(4-Methoxyphenyl)-2'-Trifluoromethylpropiophenone is a high-purity, specialized organic intermediate featuring a propiophenone core with methoxy and trifluoromethyl substituents. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients, where its unique structure imparts desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved bioactivity and environmental profile.
• Material Science Research: Used in the development of organic electronic materials, liquid crystals, and polymers where the methoxyphenyl and trifluoromethyl groups influence electronic properties and stability.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	3-(4-Methoxyphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898776-02-8
Molecular Formula	C17H15F3O2
Molecular Weight	308.30 g/mol
Synonyms	1-[3-(4-Methoxyphenyl)-1-oxopropyl]-2-(trifluoromethyl)benzene; 2'-Trifluoromethyl-3-(4-methoxyphenyl)propiophenone; 3-(4-Methoxyphenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; Propiophenone, 3-(4-methoxyphenyl)-2'-(trifluoromethyl)-; 898776-02-8; 3-(p-Methoxyphenyl)-2'-trifluoromethylpropiophenone
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxyphenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.