Description

4'-Bromo-3'-Fluoro-3-(4-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated phenylpropiophenone core.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals due to its rigid, substituted aromatic system.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other catalytic transformations in academic and industrial R&D labs.
• Fluorescent Probe Development: Its structure makes it a candidate for developing molecular probes and sensors in diagnostic applications.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(4-Methoxyphenyl)Propiophenone
CAS No.	898775-92-3
Molecular Formula	C₁₆H₁₄BrFO₂
Molecular Weight	337.19 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(4-methoxyphenyl)propan-1-one; 3-(4-Methoxyphenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoropropiophenone, 3-(4-methoxyphenyl)-; 898775-92-3; Propiophenone, 4'-bromo-3'-fluoro-3-(4-methoxyphenyl)-; 1-(4-Bromo-3-fluorophenyl)-3-(4-methoxyphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(4-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.