Description

4'-Piperidinomethyl-2-Trifluoromethylbenzophenone is a high-value, non-racemic synthetic intermediate characterized by its benzophenone core functionalized with piperidine and trifluoromethyl groups. This compound matters for its role in facilitating the synthesis of complex, biologically active molecules, offering a precise structural handle for medicinal chemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperidine and benzophenone moieties.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Item	Details
Product Name	4'-Piperidinomethyl-2-Trifluoromethylbenzophenone
CAS No.	898775-32-1
Molecular Formula	C20H20F3NO
Molecular Weight	347.38 g/mol
Synonyms	2-Trifluoromethyl-4'-(piperidinomethyl)benzophenone; [4-(Piperidin-1-ylmethyl)phenyl][2-(trifluoromethyl)phenyl]methanone; 1-({4-[2-(Trifluoromethyl)benzoyl]benzyl})piperidine; 4'-(Piperidin-1-ylmethyl)-2-(trifluoromethyl)benzophenone
EINECS	Contact for details

Quality Control

Every batch of 4'-Piperidinomethyl-2-Trifluoromethylbenzophenone is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.