Description

2',4'-Difluoro-3-(3-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring difluoro and methoxyphenyl substituents, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients with optimized properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Used in the research and development of specialty polymers and advanced organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Synthesis: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to create more complex, functionalized biphenyl and related systems for various R&D applications.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2',4'-Difluoro-3-(3-Methoxyphenyl)Propiophenone
CAS No.	898775-28-5
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	1-(2,4-Difluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3-(3-Methoxyphenyl)-1-(2,4-difluorophenyl)propan-1-one; 2,4-Difluoro-3'-(methoxy)propiophenone; 3-(3-Methoxyphenyl)-2,4-difluoropropiophenone; Propiophenone, 2',4'-difluoro-3-(3-methoxyphenyl)-; 898775-28-5; Difluoromethoxyphenyl Propiophenone Derivative
EINECS	Contact for details

Quality Control

Every batch of 2',4'-Difluoro-3-(3-Methoxyphenyl)Propiophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.