Description

2'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone is a high-value, multi-fluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate (API). Its molecular architecture, featuring a pyrrolidinomethyl side chain and a trifluoromethylphenyl moiety, makes it an essential building block for synthesizing complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new chemical entities (NCEs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies due to its fluorinated aromatic system.
• Preclinical & Clinical Trial Material: Supplied under controlled conditions for the production of materials used in non-clinical and clinical studies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	2'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone
CAS No.	898775-12-7
Molecular Formula	C18H16F3NO
Molecular Weight	319.32 g/mol
Synonyms	3,4,5-Trifluoro-2-(pyrrolidin-1-ylmethyl)benzophenone; 1-[(3,4,5-Trifluoro-2-benzoylphenyl)methyl]pyrrolidine; 2-(Pyrrolidin-1-ylmethyl)-3,4,5-trifluorobenzophenone; (3,4,5-Trifluoro-2-benzoylbenzyl)pyrrolidine; 898775-12-7; Pyrrolidinomethyl trifluorobenzophenone; TFBP-Pyrrolidine derivative
EINECS	Contact for details

Quality Control

Our 2'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.