Description

3'-Chloro-5'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and methoxy-substituted aromatic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling precise molecular construction for targeted therapeutic effects. It is primarily needed by R&D laboratories and manufacturing units in the pharmaceutical and agrochemical sectors, where it serves as a key precursor for developing new drug candidates and specialty chemicals. The product is supplied under stringent quality controls to ensure batch-to-batch consistency for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel small-molecule drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in organic synthesis for exploring new chemical entities and reaction pathways in academic and industrial settings.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and liquid crystals where specific aromatic and halogen functionalities are required.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and pilot-scale production.

Basic Information

Product Name	3'-Chloro-5'-Fluoro-3-(3-Methoxyphenyl)Propiophenone
CAS No.	898775-07-0
Molecular Formula	C16H14ClFO2
Molecular Weight	292.73 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3'-Chloro-5'-fluoro-3-(3-methoxyphenyl)propiophenone; 3-(3-Methoxyphenyl)-1-(3-chloro-5-fluorophenyl)propan-1-one; Propiophenone, 3'-chloro-5'-fluoro-3-(3-methoxyphenyl)-; 898775-07-0; 3-Chloro-5-fluoro-3'-(3-methoxyphenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.