Description

2,4-Difluoro-2'-Pyrrolidinomethyl Benzophenone is a high-value, multi-functional chemical intermediate characterized by its benzophenone core and pyrrolidinomethyl side chain. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the introduction of specific fluorinated motifs and amine functionalities into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated pharmacophores for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the difluoro and amine groups can contribute to binding affinity and environmental persistence profiles.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in OLED devices, where the benzophenone structure can influence electronic properties.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating challenging chemical transformations in fine chemical production.
• Photoinitiator & UV Absorber Development: The benzophenone moiety makes it a candidate for modifying and creating novel photoinitiators for polymer chemistry or UV-absorbing compounds for coatings and plastics.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new fluorination and amination reactions.

Basic Information

Product Name	2,4-Difluoro-2'-Pyrrolidinomethyl Benzophenone
CAS No.	898775-03-6
Molecular Formula	C18H17F2NO
Molecular Weight	301.33 g/mol
Synonyms	2,4-Difluoro-2'-(pyrrolidin-1-ylmethyl)benzophenone; 1-[(2-Benzoyl-4-fluorophenyl)methyl]pyrrolidine; 2,4-Difluoro-α-(pyrrolidin-1-ylmethyl)benzophenone; (2-Benzoyl-4-fluorophenyl)methylpyrrolidine; Benzophenone, 2,4-difluoro-2'-(pyrrolidinylmethyl)-; 898775-03-6; Pyrrolidinomethyl difluorobenzophenone derivative
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-2'-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.