Description

3-(3-Methoxyphenyl)-4'-Trifluoromethylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic and trifluoromethyl-substituted structure. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in developing novel herbicides and pesticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced organic electronic materials due to its aromatic and electron-withdrawing groups.
• Organic Synthesis & Catalysis Research: Employed in methodological studies, such as cross-coupling reactions and fluorination chemistry, to explore new synthetic pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	3-(3-Methoxyphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898775-00-3
Molecular Formula	C17H15F3O2
Molecular Weight	308.30 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-(3-methoxyphenyl)propan-1-one; 3-(3-Methoxyphenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 4'-Trifluoromethyl-3-(3-methoxyphenyl)propiophenone; 3-Methoxy-β-(4-trifluoromethylbenzoyl)styrene (precursor); 898775-00-3; Propiophenone, 3-(3-methoxyphenyl)-4'-(trifluoromethyl)-; 3-(3-Methoxyphenyl)-4'-(trifluoromethyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Methoxyphenyl)-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications, and we support audits and regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.