Description

2'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom and methoxyphenyl group can enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: Acts as a model substrate for studying fluorination reactions and the influence of fluorine on molecular conformation and reactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2'-Fluoro-3-(3-Methoxyphenyl)Propiophenone
CAS No.	898774-94-2
Molecular Formula	C16H15FO2
Molecular Weight	258.29 g/mol
Synonyms	1-(2-Fluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3-(3-Methoxyphenyl)-1-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-(3-methoxyphenyl)propiophenone; 1-Propanone, 1-(2-fluorophenyl)-3-(3-methoxyphenyl)-; 898774-94-2; Fluorinated propiophenone derivative
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.