Description

4'-Bromo-3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromo-fluoro substituted aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated halogenated building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals where specific fluorine and bromine atoms impart desired electronic or optical properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functionalization in medicinal chemistry research.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone
CAS No.	898774-86-2
Molecular Formula	C₁₆H₁₄BrFO₂
Molecular Weight	337.19 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3-(3-Methoxyphenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoro-3-(3-methoxyphenyl)propiophenone; 898774-86-2; Propiophenone, 4'-bromo-3'-fluoro-3-(3-methoxyphenyl)-; 1-Propanone, 1-(4-bromo-3-fluorophenyl)-3-(3-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.