Description

3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated biphenyl-like structure into new active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom and methoxyphenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated monomer or intermediate in the synthesis of fluorinated organic electronic materials for displays and lighting.
• Chemical Biology Probe Synthesis: Employed in creating labeled compounds and molecular probes for studying enzyme mechanisms and protein interactions.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fine Chemical Synthesis: Used as a specialty intermediate for producing flavors, fragrances, and other high-value fine chemicals requiring specific fluorinated motifs.

Basic Information

Product Name	3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone
CAS No.	898774-72-6
Molecular Formula	C16H15FO2
Molecular Weight	258.29 g/mol
Synonyms	1-(3-Fluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3'-Fluoro-3-methoxypropiophenone; 3-(3-Methoxyphenyl)-1-(3-fluorophenyl)propan-1-one; 1-Propanone, 1-(3-fluorophenyl)-3-(3-methoxyphenyl)-; 898774-72-6; 3-Fluoro-3'-methoxypropiophenone; 3-Fluoro-3-methoxydihydrochalcone
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-3-(3-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.