Description

3-(2-Methoxyphenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in modern synthetic chemistry. This compound serves as a critical intermediate for the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its unique fluorinated aromatic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for constructing complex fluorinated molecules in academic and industrial laboratories.
• Fluorine Chemistry Studies: Essential for investigating structure-activity relationships (SAR) and the effects of fluorine substitution on molecular properties and reactivity.

Basic Information

Item	Details
Product Name	3-(2-Methoxyphenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898774-19-1
Molecular Formula	C16H13F3O2
Molecular Weight	294.27 g/mol
Synonyms	1-[3,4,5-Trifluorophenyl]-3-(2-methoxyphenyl)-1-propanone; 3',4',5'-Trifluoro-3-(2-methoxyphenyl)propiophenone; 2-Methoxy-β-(3,4,5-trifluorobenzoyl)ethylbenzene; 3-(2-Methoxyphenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; Propiophenone, 3-(2-methoxyphenyl)-3',4',5'-trifluoro-
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxyphenyl)-3',4',5'-Trifluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.