Description

3',5'-Difluoro-3-(2-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring difluoro and methoxyphenyl substituents, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Utilized in the creation of fluorinated molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3',5'-Difluoro-3-(2-Methoxyphenyl)Propiophenone
CAS No.	898774-16-8
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one; 3-(2-Methoxyphenyl)-1-(3,5-difluorophenyl)-1-propanone; 3',5'-Difluoro-3-(o-methoxyphenyl)propiophenone; 2-Methoxy-β-(3,5-difluorobenzoyl)ethylbenzene; 898774-16-8; Propiophenone, 3',5'-difluoro-3-(2-methoxyphenyl)-; 3-(2-Methoxyphenyl)-1-(3,5-difluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Every batch of 3',5'-Difluoro-3-(2-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.