Description

3',4'-Difluoro-3-(2-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring difluoro and methoxy substituents, makes it a versatile and valuable precursor for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of new chemical entities, particularly in the areas of medicinal chemistry and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new generation herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers and liquid crystals, where its aromatic and fluorinated components contribute to desired material properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	3',4'-Difluoro-3-(2-Methoxyphenyl)Propiophenone
CAS No.	898774-13-5
Molecular Formula	C₁₆H₁₄F₂O₂
Molecular Weight	276.28 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one; 3-(2-Methoxyphenyl)-1-(3,4-difluorophenyl)-1-propanone; 3',4'-Difluoro-3-(2-methoxyphenyl)propiophenone; 3,4-Difluoro-3'-(2-methoxyphenyl)propiophenone; Propiophenone, 3',4'-difluoro-3-(2-methoxyphenyl)-; DFMPP (abbreviation)
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(2-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.