Description

2-Piperidinomethyl-3',4',5'-Trifluorobenzophenone is a high-value, fluorinated benzophenone derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, featuring a piperidinomethyl side chain and a trifluorinated aromatic system, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group enhances bioavailability and stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and inhibitors for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Piperidinomethyl-3',4',5'-Trifluorobenzophenone
CAS No.	898773-81-4
Molecular Formula	C20H20F3NO
Molecular Weight	347.38 g/mol
Synonyms	3',4',5'-Trifluoro-2-(piperidin-1-ylmethyl)benzophenone; 1-[(3',4',5'-Trifluorobenzoyl)benzyl]piperidine; 2-(Piperidin-1-ylmethyl)-3',4',5'-trifluorobenzophenone; (3',4',5'-Trifluorophenyl)[2-(1-piperidinylmethyl)phenyl]methanone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality system is designed to meet the exacting standards of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.