Description

3'-Chloro-5'-Fluoro-2-Piperidinomethyl Benzophenone is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. Its core value lies in its role as a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. This compound is essential for research and development chemists, process scale-up teams, and manufacturers within the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used as a structural scaffold for constructing complex molecules with potential receptor-binding activity.
• Medicinal Chemistry Research: Serves as a versatile building block for creating compound libraries in drug discovery and lead optimization programs.
• Process Development: Employed in the development and scaling of robust, cost-effective synthetic routes for target molecules.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	3'-Chloro-5'-Fluoro-2-Piperidinomethyl Benzophenone
CAS No.	898773-61-0
Molecular Formula	C19H19ClFNO
Molecular Weight	331.81 g/mol
Synonyms	2-[(Piperidin-1-yl)methyl]-3'-chloro-5'-fluorobenzophenone; 3'-Chloro-5'-fluoro-2-(piperidin-1-ylmethyl)benzophenone; Benzophenone, 3'-chloro-5'-fluoro-2-(1-piperidinylmethyl)-; 898773-61-0; 3-Chloro-5-fluoro-2-piperidin-1-ylmethyl-benzophenone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-Fluoro-2-Piperidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.