Description

3'-Azetidinomethyl-3,4-Difluorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique azetidine and difluorobenzophenone structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile chemical scaffold.
• API Synthesis: Serves as a precursor in the multi-step manufacturing of complex target molecules for clinical trials.
• Chemical Biology Probes: Utilized in the development of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring specialized fluorinated intermediates.

Basic Information

Product Name	3'-Azetidinomethyl-3,4-Difluorobenzophenone
CAS No.	898772-24-2
Molecular Formula	C17H15F2NO
Molecular Weight	287.31 g/mol
Synonyms	3,4-Difluoro-3'-(azetidin-1-ylmethyl)benzophenone; 1-[(3-Benzoyl-2,6-difluorophenyl)methyl]azetidine; 3'-(Azetidin-1-ylmethyl)-3,4-difluorobenzophenone; Azetidine, 1-[(3-benzoyl-2,6-difluorophenyl)methyl]-; 898772-24-2; 3'-Azetidin-1-ylmethyl-3,4-difluorobenzophenone
EINECS	Contact for details

Quality Control

Our 3'-Azetidinomethyl-3,4-Difluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.