Description

3'-Azetidinomethyl-2,4-Difluorobenzophenone is a high-value pharmaceutical intermediate characterized by its unique azetidine and difluorobenzophenone structure. This compound matters as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. Pharmaceutical R&D departments and fine chemical manufacturers need this precise intermediate to develop novel therapeutic agents with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Synthesis: Used in the construction of complex molecular scaffolds for potential Active Pharmaceutical Ingredients targeting specific biological receptors.
• Chemical Biology Research: Serves as a versatile probe or building block in the development of chemical tools for studying biological mechanisms.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3'-Azetidinomethyl-2,4-Difluorobenzophenone
CAS No.	898772-21-9
Molecular Formula	C17H15F2NO
Molecular Weight	287.31 g/mol
Synonyms	2,4-Difluoro-3'-(azetidin-1-ylmethyl)benzophenone; 1-[(2,4-Difluorophenyl)(phenyl)methyl]azetidine; 3'-(Azetidin-1-ylmethyl)-2,4-difluorobenzophenone; 898772-21-9; (2,4-Difluorophenyl)[3-(azetidin-1-ylmethyl)phenyl]methanone
EINECS	Contact for details

Quality Control

Our 3'-Azetidinomethyl-2,4-Difluorobenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. Each lot undergoes comprehensive analytical testing including HPLC purity assay, residual solvent analysis, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.