Description

3'-Azetidinomethyl-3-Chloro-4-Fluorobenzophenone is a high-purity advanced pharmaceutical intermediate (API intermediate) characterized by its distinct benzophenone core functionalized with azetidine, chlorine, and fluorine substituents. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to develop next-generation drug candidates, leveraging its unique structure to modulate biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and scale-up production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Chemical Research: Serves as a versatile scaffold in organic synthesis and process chemistry for creating libraries of compounds with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Life Science Reagents: May be utilized in biochemical research as a specialized reagent or probe for studying enzyme interactions or cellular pathways.

Basic Information

Product Name	3'-Azetidinomethyl-3-Chloro-4-Fluorobenzophenone
CAS No.	898771-85-2
Molecular Formula	C17H15ClFNO
Molecular Weight	303.76 g/mol
Synonyms	3-Chloro-4-fluoro-3'-(azetidin-1-ylmethyl)benzophenone; 1-({[3-Chloro-4-fluoro-3'-(phenylcarbonyl)phenyl]methyl})azetidine; 3'-Azetidin-1-ylmethyl-3-chloro-4-fluorobenzophenone; 3-Chloro-4-fluoro-3'-(azetidinomethyl)benzophenone; (3-Chloro-4-fluorophenyl)[3-(azetidin-1-ylmethyl)phenyl]methanone; Azetidine, 1-[[3-chloro-4-fluoro-3'-(phenylcarbonyl)phenyl]methyl]-; Benzophenone, 3'-azetidinomethyl-3-chloro-4-fluoro-
EINECS	Contact for details

Quality Control

Our 3'-Azetidinomethyl-3-Chloro-4-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications, ensuring traceability and compliance for advanced R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.