Description

3'-Azetidinomethyl-4-Chloro-3-Fluorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique azetidine and benzophenone structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic targets.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for clinical trial material.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Employed in university and institutional labs for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	3'-Azetidinomethyl-4-Chloro-3-Fluorobenzophenone
CAS No.	898771-83-0
Molecular Formula	C17H15ClFNO
Molecular Weight	303.76 g/mol
Synonyms	4-Chloro-3-fluoro-3'-(azetidin-1-ylmethyl)benzophenone; 1-[(4-Chloro-3-fluorobenzoyl)phenylmethyl]azetidine; 3'-(Azetidin-1-ylmethyl)-4-chloro-3-fluorobenzophenone; (4-Chloro-3-fluorophenyl){3-[(azetidin-1-yl)methyl]phenyl}methanone; Azetidine, 1-[[(4-chloro-3-fluorophenyl)phenylmethylene]methyl]-; 898771-83-0; 3'-Azetidin-1-ylmethyl-4-chloro-3-fluorobenzophenone
EINECS	Contact for details

Quality Control

Our 3'-Azetidinomethyl-4-Chloro-3-Fluorobenzophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development needs with custom purity grades and can provide material suitable for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.