Description

3-Azetidinomethyl-4'-Fluorobenzophenone CAS NO 898771-67-0 is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine moiety. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Custom Synthesis: Basis for the preparation of labeled compounds (e.g., deuterated or C14-labeled) for pharmacokinetic and metabolic studies.

Basic Information

Product Name	3-Azetidinomethyl-4'-Fluorobenzophenone
CAS No.	898771-67-0
Molecular Formula	C17H16FNO
Molecular Weight	269.32 g/mol
Synonyms	4'-Fluoro-3-(azetidin-1-ylmethyl)benzophenone; 1-[(4-Fluorophenyl)(phenyl)methyl]azetidine; 3-(Azetidin-1-ylmethyl)-4'-fluorobenzophenone; (4-Fluorophenyl)(phenyl)methanone, 3-(azetidin-1-ylmethyl)-; Azetidine, 1-[(4-fluorophenyl)phenylmethyl]-; 898771-67-0; 4'-Fluoro-3-azetidin-1-ylmethyl-benzophenone
EINECS	Contact for details

Quality Control

Our 3-Azetidinomethyl-4'-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.