Description

3-(4-Chloro-2-Fluorobenzoyl)Thiophene is a high-purity organic building block characterized by its unique halogenated benzoyl-thiophene structure. This compound is of significant value in advanced organic synthesis, serving as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogen-substituted aromatic system for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to the thiophene moiety.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a scaffold for creating more complex heterocyclic compounds in medicinal chemistry.
• Life Science Research: Utilized as a reference standard or biochemical tool in academic and industrial R&D for probing biological pathways.

Basic Information

Product Name	3-(4-Chloro-2-Fluorobenzoyl)Thiophene
CAS No.	898771-47-6
Molecular Formula	C11H6ClFOS
Molecular Weight	240.68 g/mol
Synonyms	3-(4-Chloro-2-fluorobenzoyl)thiophene; 4-Chloro-2-fluoro-3-thienyl phenyl ketone; (4-Chloro-2-fluorophenyl)(thiophen-3-yl)methanone; Thiophene, 3-(4-chloro-2-fluorobenzoyl)-; 898771-47-6; 3-(4-Chloro-2-fluoro-benzoyl)-thiophene; 3-(4-Chloro-2-fluorobenzoyl)thiophene, 98%
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-2-Fluorobenzoyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.