Description

3-(2-Trifluoromethylbenzoyl)Thiophene is a high-value fluorinated aromatic ketone building block, specifically designed for advanced organic synthesis. This compound matters for its unique trifluoromethyl-substituted benzoyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to unique optical and electronic properties.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for high-performance display technologies.
• Chemical Biology Probes: Useful for labeling and studying biological processes due to its distinct spectroscopic signature.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	3-(2-Trifluoromethylbenzoyl)Thiophene
CAS No.	898771-30-7
Molecular Formula	C12H7F3OS
Molecular Weight	256.24 g/mol
Synonyms	3-(2-(Trifluoromethyl)benzoyl)thiophene; 2-Trifluoromethyl-3-benzoylthiophene; 1-(Thiophen-3-yl)-2-(trifluoromethyl)phenyl)methanone; 3-Benzoyl-2-(trifluoromethyl)thiophene; Thiophene, 3-[2-(trifluoromethyl)benzoyl]-; α-(2-Trifluoromethylphenyl)-3-thienyl ketone
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Trifluoromethylbenzoyl)Thiophene is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.