Description

3'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone is a high-value, fluorinated benzophenone derivative that serves as a critical advanced pharmaceutical intermediate (API intermediate). Its molecular structure, featuring a pyrrolidinomethyl side chain and trifluoromethyl substituents, makes it a key building block for synthesizing complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in drug discovery and lead optimization programs to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• Process Chemistry & Scale-Up: Serves as a key starting material or intermediate in the development and optimization of scalable synthetic routes for potential drug candidates.
• Agrochemical Intermediate: Potential use in the research and synthesis of advanced agrochemicals, leveraging the biological activity often associated with fluorinated aromatic compounds.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex organic molecules requiring its specific trifluoromethyl and ketone functionalities.

Basic Information

Product Name	3'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone
CAS No.	898770-92-8
Molecular Formula	C18H16F3NO
Molecular Weight	319.32 g/mol
Synonyms	3,4,5-Trifluoro-3'-(pyrrolidin-1-ylmethyl)benzophenone; 1-({[3,4,5-Trifluorophenyl](phenyl)carbonyl}methyl)pyrrolidine; 3,4,5-Trifluoro-3'-(pyrrolidinomethyl)benzophenone; (3,4,5-Trifluorophenyl)[3-(pyrrolidin-1-ylmethyl)phenyl]methanone; 898770-92-8; 3'-Pyrrolidinylmethyl-3,4,5-trifluorobenzophenone
EINECS	Contact for details

Quality Control

Our 3'-Pyrrolidinomethyl-3,4,5-Trifluorobenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, GC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of our global clientele in the pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.