Description

3,5-Difluoro-3'-Pyrrolidinomethyl Benzophenone is a high-value, functionalized benzophenone derivative designed for advanced chemical synthesis. This compound matters as a versatile building block, offering a unique combination of a benzophenone core, fluorine substituents, and a pyrrolidinomethyl group, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, especially in kinase inhibitor and protease inhibitor programs.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies to introduce fluorinated motifs and basic amine functionalities into lead compounds.
• Agrochemical Synthesis: Employed in the development of new herbicides and pesticides, where the fluorine atoms can enhance metabolic stability and bioavailability.
• Material Science Research: Acts as a precursor or monomer in the synthesis of specialty polymers and advanced organic materials.
• Photoinitiator Development: The benzophenone core makes it a candidate for research into novel photoinitiators for UV-curable coatings and resins.
• Chemical Biology Probes: Utilized in the design of photoaffinity labeling probes and other tools for studying biological systems and target identification.

Basic Information

Product Name	3,5-Difluoro-3'-Pyrrolidinomethyl Benzophenone
CAS No.	898770-90-6
Molecular Formula	C19H19F2NO
Molecular Weight	315.36 g/mol
Synonyms	3,5-Difluoro-3'-(pyrrolidin-1-ylmethyl)benzophenone; 1-({3-[(3,5-Difluorophenyl)carbonyl]phenyl}methyl)pyrrolidine; Benzophenone, 3,5-difluoro-3'-(pyrrolidinylmethyl)-; 3,5-Difluoro-3'-(1-pyrrolidinylmethyl)benzophenone; 898770-90-6; 3'-(Pyrrolidin-1-ylmethyl)-3,5-difluorobenzophenone
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-3'-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.