Description

4-Bromo-2-Fluoro-3'-Pyrrolidinomethyl Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzophenone structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential protease inhibitors, leveraging the pyrrolidinomethyl moiety.
• Kinase Inhibitor Synthesis: Employed as a building block for creating targeted kinase inhibitors, a major class in oncology therapeutics.
• Chemical Biology Probes: Utilized in the design and creation of chemical probes for studying specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4-Bromo-2-Fluoro-3'-Pyrrolidinomethyl Benzophenone
CAS No.	898770-68-8
Molecular Formula	C18H17BrFNO
Molecular Weight	362.24 g/mol
Synonyms	4-Bromo-2-fluoro-3'-(pyrrolidin-1-ylmethyl)benzophenone; 3'-(Pyrrolidin-1-ylmethyl)-4-bromo-2-fluorobenzophenone; Benzophenone, 4-bromo-2-fluoro-3'-(pyrrolidin-1-ylmethyl)-; 898770-68-8; 4-Bromo-2-fluoro-3'-pyrrolidin-1-ylmethylbenzophenone
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-3'-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with ICH guidelines for pharmaceutical intermediates, supporting our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.