Description

3-Pyrrolidinomethyl-4'-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular scaffold. This compound is critical for research and development in medicinal chemistry, particularly for constructing molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of specific enzymes, such as kinases or proteases.
• Chemical Library Synthesis: Employed in combinatorial chemistry to create diverse compound libraries for high-throughput screening.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke molecules for client projects.

Basic Information

Product Name	3-Pyrrolidinomethyl-4'-Trifluoromethylbenzophenone
CAS No.	898770-66-6
Molecular Formula	C19H18F3NO
Molecular Weight	333.35 g/mol
Synonyms	4'-Trifluoromethyl-3-pyrrolidinomethylbenzophenone; 3-(Pyrrolidin-1-ylmethyl)-4'-(trifluoromethyl)benzophenone; 1-[(4-Benzoyl-2-(trifluoromethyl)phenyl)methyl]pyrrolidine; (4'-Trifluoromethyl-biphenyl-3-yl)-pyrrolidin-1-yl-methanone (related structural isomer); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinomethyl-4'-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.