Description

4'-Bromo-2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate with a complex aromatic ketone structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing fluorinated and brominated aromatic systems to study structure-activity relationships (SAR).
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Research: Potential intermediate for developing new generation fluorinated agrochemicals with enhanced biological activity and stability.
• Material Science Precursor: Can be utilized in the synthesis of specialized organic ligands and monomers for advanced polymeric materials.

Basic Information

Product Name	4'-Bromo-2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone
CAS No.	898770-36-0
Molecular Formula	C₁₆H₁₄BrFO₂
Molecular Weight	337.19 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-3-(2-methoxyphenyl)propan-1-one; 3-(2-Methoxyphenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one; 4'-Bromo-2'-fluoro-3-(2-methoxyphenyl)propiophenone; 898770-36-0; Propiophenone, 4'-bromo-2'-fluoro-3-(2-methoxyphenyl)-; 1-Propanone, 1-(4-bromo-2-fluorophenyl)-3-(2-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.