Description

4'-Fluoro-3-Pyrrolidinomethyl Benzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique pyrrolidinomethyl side chain and fluorine substitution, which are key structural motifs for modulating biological activity and pharmacokinetic properties in drug discovery. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance stability and bioavailability.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and protein-ligand interactions.
• Material Science Precursor: Can serve as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for medicinal chemistry and process development projects.

Basic Information

Product Name	4'-Fluoro-3-Pyrrolidinomethyl Benzophenone
CAS No.	898770-31-5
Molecular Formula	C18H18FNO
Molecular Weight	283.34 g/mol
Synonyms	4'-Fluoro-3-(pyrrolidin-1-ylmethyl)benzophenone; 3-[(Pyrrolidin-1-yl)methyl]-4'-fluorobenzophenone; 1-[(4-Fluorophenyl){3-[(pyrrolidin-1-yl)methyl]phenyl}methanone; Benzophenone, 4'-fluoro-3-(1-pyrrolidinylmethyl)-; 898770-31-5
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.