Description

3-(2-Methoxyphenyl)-3'-Trifluoromethylpropiophenone is a high-value, fluorinated aromatic ketone building block. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring trifluoromethyl groups for metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoromethyl moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for the development of fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial research labs for developing new synthetic methodologies, such as cross-coupling reactions or asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	3-(2-Methoxyphenyl)-3'-Trifluoromethylpropiophenone
CAS No.	898770-30-4
Molecular Formula	C17H15F3O2
Molecular Weight	308.30 g/mol
Synonyms	1-[3-(2-Methoxyphenyl)-3-oxopropyl]-4-(trifluoromethyl)benzene; 3-Oxo-3-(2-methoxyphenyl)-1-[4-(trifluoromethyl)phenyl]propane; 3-(2-Methoxyphenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 2-Methoxy-β-oxo-β-(4-trifluoromethylphenyl)propiophenone; 3-(2-Methoxyphenyl)-3'-(trifluoromethyl)propiophenone; Propiophenone, 3-(2-methoxyphenyl)-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxyphenyl)-3'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.