Description

3-(2-Methoxyphenyl)-2'-Trifluoromethylpropiophenone is a high-value, specialized organic intermediate featuring a propiophenone core substituted with methoxyphenyl and trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents, where the trifluoromethyl group is prized for enhancing metabolic stability and bioavailability. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl moiety.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, or specialty polymers where its specific aromatic and fluorinated structure can tune electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new synthetic pathways for complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale clinical trial materials.

Basic Information

Product Name	3-(2-Methoxyphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898770-27-9
Molecular Formula	C17H15F3O2
Molecular Weight	308.30 g/mol
Synonyms	1-[3-(2-Methoxyphenyl)-1-oxopropyl]-2-(trifluoromethyl)benzene; 2'-Trifluoromethyl-3-(2-methoxyphenyl)propiophenone; 3-(2-Methoxyphenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; α-Methyl-2'-trifluoromethyl-3-(o-methoxyphenyl)propiophenone; Propiophenone, 3-(2-methoxyphenyl)-2'-(trifluoromethyl)-; 898770-27-9
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxyphenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.