Description

2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom and methoxyphenyl group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, where its specific substitution pattern influences electronic properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) exploring new chemical entities.
• Fluorine Chemistry Studies: A valuable substrate for studying the influence of fluorine substitution on reaction kinetics and molecular conformation in organic synthesis.

Basic Information

Product Name	2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone
CAS No.	898770-24-6
Molecular Formula	C16H15FO2
Molecular Weight	258.29 g/mol
Synonyms	1-(2-Fluorophenyl)-3-(2-methoxyphenyl)propan-1-one; 3-(2-Methoxyphenyl)-1-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-(2-methoxyphenyl)propiophenone; β-(2-Methoxyphenyl)-2'-fluoropropiophenone; Propiophenone, 2'-fluoro-3-(2-methoxyphenyl)-; 898770-24-6; 2-Fluoro-β-(2-methoxyphenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.