Description

4'-Bromo-3'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate with a complex aromatic ketone structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process chemistry optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Organic Synthesis Research: Used in academic and industrial R&D for studying cross-coupling reactions, fluorination effects, and ketone chemistry.
• Agrochemical Development: Serves as a precursor in the research and development of new-generation pesticides and herbicides with enhanced efficacy.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(2-Methoxyphenyl)Propiophenone
CAS No.	898770-12-2
Molecular Formula	C₁₆H₁₄BrFO₂
Molecular Weight	337.19 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(2-methoxyphenyl)propan-1-one; 3-(2-Methoxyphenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoro-3-(2-methoxyphenyl)propiophenone; 898770-12-2; Propiophenone, 4'-bromo-3'-fluoro-3-(2-methoxyphenyl)-; 1-(4-Bromo-3-fluorophenyl)-3-(2-methoxyphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(2-Methoxyphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.