Description

Cyclohexyl 2,4-Difluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its difluorophenyl and ketone functionalities enable precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into active molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis & Catalysis Research: A valuable substrate in methodological studies for developing new fluorination, cross-coupling, and carbonyl transformation reactions.
• Material Science Research: Investigated for creating novel fluorinated ligands for metal-organic frameworks (MOFs) or other functional materials.

Basic Information

Product Name	Cyclohexyl 2,4-Difluorophenyl Ketone
CAS No.	898769-54-5
Molecular Formula	C13H14F2O
Molecular Weight	224.25 g/mol
Synonyms	2',4'-Difluorocyclohexyl Phenyl Ketone; (2,4-Difluorophenyl)(cyclohexyl)methanone; Cyclohexyl(2,4-difluorophenyl)methanone; 1-Cyclohexyl-2,4-difluoro-1-phenylethanone; 898769-54-5; Cyclohexyl 2,4-difluorobenzoyl; Ketone, cyclohexyl 2,4-difluorophenyl
EINECS	Contact for details

Quality Control

Our Cyclohexyl 2,4-Difluorophenyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.