Description

3-Chloro-5-Fluorophenyl Cyclohexyl Ketone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the creation of novel agrochemicals, active pharmaceutical ingredients (APIs), and specialty liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and pesticides, where the fluorine and chlorine substituents enhance biological activity and stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated liquid crystal compounds for high-performance display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as an intermediate for electron-transport or host materials in OLED device fabrication.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and novel fluorination reactions.
• Specialty Polymer Modification: Can be utilized to introduce specific aromatic ketone functionalities into polymer backbones for specialized material properties.

Basic Information

Product Name	3-Chloro-5-Fluorophenyl Cyclohexyl Ketone
CAS No.	898769-36-3
Molecular Formula	C₁₃H₁₄ClFO
Molecular Weight	240.70 g/mol
Synonyms	Cyclohexyl 3-Chloro-5-fluorophenyl ketone; 3-Chloro-5-fluorophenyl cyclohexyl ketone; 1-(3-Chloro-5-fluorophenyl)cyclohexan-1-ol (tautomer); 3-Chloro-5-fluoro-cyclohexylphenylmethanone; 898769-36-3; 3-Chloro-5-fluorobenzoylcyclohexane; (3-Chloro-5-fluorophenyl)(cyclohexyl)methanone
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-5-Fluorophenyl Cyclohexyl Ketone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality system that supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.