Description

2-Chloro-4-Fluorophenyl Cyclohexyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways due to its modifiable ketone functionality.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Chloro-4-Fluorophenyl Cyclohexyl Ketone
CAS No.	898769-33-0
Molecular Formula	C13H14ClFO
Molecular Weight	240.70 g/mol
Synonyms	Cyclohexyl 2-Chloro-4-fluorophenyl ketone; 2-Chloro-4-fluoro-cyclohexylphenylmethanone; 1-(2-Chloro-4-fluorophenyl)cyclohexan-1-one; (2-Chloro-4-fluorophenyl)(cyclohexyl)methanone; 898769-33-0; Ketone, 2-chloro-4-fluorophenyl cyclohexyl
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorophenyl Cyclohexyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.