Description

4-Chloro-3-Fluorophenyl Cyclohexyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and R&D chemists need it for constructing active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals where its specific halogenated pattern is critical for bioactivity and material properties.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances efficacy.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores used in electronic display technologies and organic semiconductors.
• Advanced Polymer Modification: Incorporated as a monomer or modifier to impart specific thermal, optical, or chemical resistance properties to high-performance engineering plastics.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways in organofluorine chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	4-Chloro-3-Fluorophenyl Cyclohexyl Ketone
CAS No.	898769-24-9
Molecular Formula	C₁₃H₁₄ClFO
Molecular Weight	240.70 g/mol
Synonyms	Cyclohexyl(4-chloro-3-fluorophenyl)methanone; 4-Chloro-3-fluorophenyl cyclohexyl ketone; 1-(4-Chloro-3-fluorophenyl)-1-cyclohexanone; (4-Chloro-3-fluorophenyl)(cyclohexyl)methanone; 898769-24-9; 4-Chloro-3-fluoro cyclohexyl phenyl ketone; 4'-Chloro-3'-fluorocyclohexyl phenyl ketone
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorophenyl Cyclohexyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Maximum Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.